5-LOX Inhibitor with AprèsFlex®, 100 mg, 60 vegetarian capsules - Life Extension
Boswellia
100 mg, 60 vegetarian capsules
Item # 01639
UPC: 737870163961
Promotes joint, cell & arterial health.
4.6
Standardized Boswellia serrata extract that promotes a healthy inflammatory response and absorbs 52% better than standard boswellia extracts.
Gluten free
Non-GMO
Vegetarian
Supplements by Health Goal:
Overview
What Is Boswellia?
Compounds in Boswellia extract have been shown to bind directly to 5-LOX, an enzyme that transforms fatty acids into inflammatory factors like leukotriene B4. A compound in boswellia called AKBA is the key to this beneficial action. Each 100 mg vegetarian capsule of Boswellia is standardized to provide 20% of active AKBA from boswellia.
Boswellia Benefits
- Promotes a healthy inflammatory response by inhibiting 5-LOX enzyme
- Supports joint health, arterial health & healthy cell division
Better-Absorbed Boswellia
Boswellia is an extract that can inhibit inflammatory factors to support joint and arterial health. In this supplement, we use a standardized form of boswellia called AprèsFlex® that absorbs into the blood 52 percent more than previously available boswellia extracts. Each vegetarian capsule of Boswellia with AprèsFlex® provides 100 mg of this innovative extract.
Product Details
5-lipoxygenase (5-LOX) is an enzyme that transforms fatty acids into leukotrienes. Since 5-LOX levels increase over time, excess 5-LOX has been linked to some of the common effects of normal aging.
Boswellia extract inhibits 5-LOX
The Indian plant Boswellia serrata contains compounds shown to inhibit 5-LOX to support joint and arterial health. Boswellia inhibits 5-LOX at the cellular level. Scientific data reveals that a compound in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid) is the key to this beneficial action.
Dietary factors increase 5-LOX prevalence
The typical American diet adds to 5-LOX levels. Foods rich in omega-6 fatty acids trigger production of arachidonic acid. The body produces 5-LOX enzyme in response to arachidonic acid.
Benefits of modulating 5-LOX
5-LOX creates compounds like leukotriene B4 out of arachidonic acid. Inhibiting leukotriene B4 helps support joint, arterial and tissue health. Inhibiting 5-LOX also helped support healthy cell division in preclinical models. Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia. Most people need only one capsule a day.
Supplement Facts
| Serving Size | 1 vegetarian capsule |
|---|---|
| Amount Per Serving | |
| AprèsFlex® ( Boswellia serrata) extract (gum resin) | |
| (std. to 20% 3-O-acetyl-11-keto-ß-boswellic acid (AKBA)) | 100 mg |
| Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate. |
Warnings
- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
References
- Biochim Biophys Acta - Molecular and Cell Biology of Lipids. 2015;1851(4):331-339.
- FASEB J. 2000;14(10):1464-1469.
- Clin Pharmacokinet. 2011;50(6):349-369.
- Mol Cell Biol. 2011;354(1):189-197.
- Semin Immunol. 2017;33:3-15.
- Clin Cancer Res. 2005;11(5):2089.